Guidelines

Topics

The guidelines (evidence and recommendations) for the long-term follow-up of childhood, adolescent and young adult cancer survivors for the specific late effects can be found in the left menu.

For every topic the underlying evidence and recommendations are presented.

The recommendations are categorized using a 4-color grading system:

• Green represents a strong recommendation.
• Yellow and orange represent moderate recommendations with a higher degree of uncertainty, meaning that other factors, such as the clinical scenario, family history, patient preferences, costs and relevant risk factors need to be considered in the decision-making process.
• Red is used to recommend against a particular intervention, with harms outweighing the benefits.

Guidelines developed to date include: 

• Bone mineral density surveillance
• Breast cancer surveillance
• Cardiomyopathy surveillance
• Central nervous system neoplasm surveillance
• Coronary artery disease surveillance
• Dexrazoxane cardioprotection
• Fatigue surveillance
• Fertility preservation
• Hepatic toxicity surveillance
• Hypothalamic-pituitary dysfunction surveillance
• Male gonadotoxicity surveillance
• Mental health problems surveillance
• Obstetric care
• Ototoxicity surveillance
• Premature ovarian insufficiency surveillance, update in progress
• Psychosocial problems surveillance
• Pulmonary dysfunction surveillance
• Thyroid cancer surveillance
• COVID-19 statement

Guidelines in progress include:

• Colorectal cancer surveillance
• Health promotion
• Growth hormone treatment
• Metabolic syndrome surveillance
• Nephrotoxicity surveillance
• Neurocognitive problems surveillance
• Premature ovarian insufficiency surveillance update
• Splenic dysfunction surveillance
• Anthracycline cardiotoxicity equivalence ratio